CKDdb-logoCKDdb - Molecule ID A267A

geneCAND1, TIP120, TIP120A
nameCullin-associated NEDD8-dissociated protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAND1_HUMANQ86VP6ENSP0000044408955832Hs.546407607727

Functions and classifications

GOC:cullin-RING ubiquitin ligase complex, C:cytoplasm, C:nucleus, P:cell differentiation, P:negative regulation of catalytic activity, P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly, P:protein ubiquitination, P:SCF complex assembly, C:nucleus, C:ubiquitin ligase complex, P:transcription, DNA-dependent
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, Direct protein sequencing, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Ubl conjugation pathway, Transcription, Transcription regulation
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.29< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium