CKDdb-logoCKDdb - Molecule ID A257F

geneAF10, MLLT10, MLL/AF10 fusion
nameAF-10 protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AF10_HUMANP55197ENSG000000784038028Hs.30385602409

Functions and classifications

GOC:cytoplasm, C:nucleus, F:DNA binding, F:sequence-specific DNA binding transcription factor activity, F:zinc ion binding, P:positive regulation of transcription from RNA polymerase II promoter, P:transcription, DNA-templated, C:cytoplasm, F:metal ion binding, P:transcription, DNA-dependent
UniProtAlternative splicing, Chromosomal rearrangement, Complete proteome, DNA-binding, Metal-binding, Nucleus, Phosphoprotein, Proto-oncogene, Reference proteome, Repeat, Transcription, Transcription regulation, Zinc, Zinc-finger
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.430.0191RNA microarray19698090
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.20.014716RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium