CKDdb-logoCKDdb - Molecule ID A2504

geneATF1
nameCyclic-AMP-dependent transcription factor ATF-1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATF1_HUMANP18846ENSG00000123268466Hs.648565123803, 612160

Functions and classifications

GOC:nucleoplasm, C:transcription factor complex, F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, F:sequence-specific DNA binding, F:sequence-specific DNA binding transcription factor activity, P:cellular protein complex assembly, P:innate immune response, P:MyD88-dependent toll-like receptor signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:positive regulation of DNA replication, P:positive regulation of neuron projection development, P:positive regulation of transcription from RNA polymerase II promoter, P:response to cobalt ion, P:response to organic cyclic compound, P:stress-activated MAPK cascade, P:toll-like receptor 10 signaling pathway, P:toll-like receptor 2 signaling pathway, P:toll-like receptor 3 signaling pathway, P:toll-like receptor 4 signaling pathway, P:toll-like receptor 5 signaling pathway, P:toll-like receptor 9 signaling pathway, P:toll-like receptor TLR1:TLR2 signaling pathway, P:toll-like receptor TLR6:TLR2 signaling pathway, P:transcription from RNA polymerase II promoter, P:TRIF-dependent toll-like receptor signaling pathway, C:nucleus, P:nerve growth factor receptor signaling pathway, P:Toll signaling pathway, P:toll-like receptor 1 signaling pathway
UniProtActivator, Chromosomal rearrangement, Complete proteome, DNA-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Transcription, Transcription regulation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.030.000213RNA microarray19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.497.95E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium