CKDdb-logoCKDdb - Molecule ID A2503

geneATF6
nameCyclic-AMP-dependent transcription factor ATF-6 alpha
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATF6A_HUMANP18850ENSG0000011821722926Hs.492740605537

Functions and classifications

GOC:endoplasmic reticulum membrane, C:Golgi membrane, C:integral component of membrane, C:nuclear envelope, C:nucleoplasm, F:sequence-specific DNA binding, F:sequence-specific DNA binding transcription factor activity, F:transcription coactivator activity, P:activation of signaling protein activity involved in unfolded protein response, P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response, P:protein folding, P:transcription, DNA-templated, C:integral to membrane, P:transcription, DNA-dependent"
UniProtActivator, Complete proteome, DNA-binding, Endoplasmic reticulum, Glycoprotein, Membrane, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Signal-anchor, Transcription, Transcription regulation, Transmembrane, Transmembrane helix, Unfolded protein response
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.473.08E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium