CKDdb-logoCKDdb - Molecule ID A2502

geneATF6B, CREBL1, G13
nameCyclic-AMP-dependent transcription factor ATF-6 beta
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATF6B_HUMANQ99941ENSG000001684681388Hs.42853600984

Functions and classifications

GOC:endoplasmic reticulum membrane, C:focal adhesion, C:integral component of membrane, C:nucleolus, F:sequence-specific DNA binding, F:sequence-specific DNA binding transcription factor activity, P:response to unfolded protein, P:signal transduction, P:transcription, DNA-templated, C:integral to membrane, P:transcription, DNA-dependent
UniProtAcetylation, Activator, Alternative splicing, Complete proteome, DNA-binding, Endoplasmic reticulum, Glycoprotein, Membrane, Nucleus, Reference proteome, Signal-anchor, Transcription, Transcription regulation, Transmembrane, Transmembrane helix, Unfolded protein response
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.40.0139RNA microarray19698090
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.322.36E-08RNA microarray24569379
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.318.96E-04RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)3.937.55E-06RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)4.240.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium