CKDdb-logoCKDdb - Molecule ID A249F

geneADM2, AM2
nameIntermedin
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADM2_HUMANQ7Z4H4ENSG0000012816579924Hs.449099608682

Functions and classifications

GOC:extracellular region, F:protein complex binding, P:adenylate cyclase-activating G-protein coupled receptor signaling pathway, P:angiogenesis, P:digestion, P:feeding behavior, P:negative regulation of blood pressure, P:positive regulation of angiogenesis, P:positive regulation of gene expression, P:protein phosphorylation
UniProtAmidation, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, Hormone, Reference proteome, Secreted, Signal
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.250.000415RNA microarray19698090
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.30.00207RNA microarray23291264
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.390.00758RNA microarray23291264

Compile date 08-10-2018© iMODE-CKD consortium