CKDdb-logoCKDdb - Molecule ID A2496

geneATF3, ATF3deltaZip2exonD'DE'E, ATF3deltaZip2a
nameCyclic-AMP-dependent transcription factor ATF-3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATF3_HUMANP18847ENSG00000162772467Hs.460603148

Functions and classifications

GOC:nucleolus, C:nucleoplasm, F:sequence-specific DNA binding, F:sequence-specific DNA binding transcription factor activity, F:transcription corepressor activity, P:activation of signaling protein activity involved in unfolded protein response, P:cellular protein metabolic process, P:gluconeogenesis, P:negative regulation of transcription, DNA-templated, P:positive regulation of cell proliferation, P:skeletal muscle cell differentiation, P:transcription, DNA-templated, P:skeletal muscle cell differentiation, C:nucleus, P:negative regulation of transcription, DNA-dependent, P:transcription, DNA-dependent, P:positive regulation of cell proliferation, C:nucleus
UniProtAlternative splicing, Complete proteome, DNA-binding, Nucleus, Polymorphism, Reference proteome, Repressor, Transcription, Transcription regulation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18187931aMus musculus20kidneyglomeruliGlomerulonephritis (lupus nephritis)4.6< 0.05RNA microarray18187931
Exp18187931bMus musculus18kidneyglomeruliGlomerulonephritis (lupus nephritis)3< 0.05RNA microarray18187931
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)5.140.0000106RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.143.23E-06RNA microarray20019191
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)3.950.00000267RNA microarray24569379
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)2.922.30E-03RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)3.65.61E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium