CKDdb-logoCKDdb - Molecule ID A2481

nameArylsulfatase A precursor
speciesHomo sapiens

Molecule reference

ARSA_HUMANP15289ENSP00000216124410Hs.731715250100, 272200, 607574

Functions and classifications

GOC:acrosomal vesicle, C:endoplasmic reticulum lumen, C:endosome, C:extracellular space, C:extrinsic component of external side of plasma membrane, C:integral component of membrane, C:lysosomal lumen, F:arylsulfatase activity, F:calcium ion binding, F:cerebroside-sulfatase activity, P:autophagy, P:binding of sperm to zona pellucida, P:central nervous system development, P:glycosphingolipid metabolic process, P:post-translational protein modification, P:response to estrogen, P:response to ethanol, P:response to methylmercury, P:response to nutrient, P:response to pH, P:small molecule metabolic process, F:sulfuric ester hydrolase activity, C:plasma membrane, P:phospholipid metabolic process
UniProt3D-structure, Alternative splicing, Calcium, Complete proteome, Direct protein sequencing, Disease mutation, Disulfide bond, Glycoprotein, Hydrolase, Ichthyosis, Leukodystrophy, Lysosome, Metachromatic leukodystrophy, Metal-binding, Polymorphism, Reference proteome, Signal
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseDetectionPubMed/DOI
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection)0.3LC-MS/MS20543976
Exp24096133bHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy)2.111DE, MALDI24096133
Exp24096133fHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes with retinopathy)0.471DE, MALDI24096133

Compile date 08-10-2018© iMODE-CKD consortium