CKDdb-logoCKDdb - Molecule ID A246A

geneARNTL2, BHLHE6, BMAL2
nameAryl hydrocarbon receptor nuclear translocator-like protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BMAL2_HUMANQ8WYA1ENSG0000002915356938Hs.434269614517

Functions and classifications

GOC:cytoplasm, C:nucleus, C:transcription factor complex, F:DNA binding, F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, F:signal transducer activity, P:circadian rhythm, P:entrainment of circadian clock, P:positive regulation of transcription from RNA polymerase II promoter, C:cytoplasm, F:sequence-specific DNA binding transcription factor activity, P:transcription, DNA-templated, P:transcription, DNA-dependent
UniProt3D-structure, Activator, Alternative splicing, Biological rhythms, Complete proteome, DNA-binding, Nucleus, Polymorphism, Reference proteome, Repeat, Transcription, Transcription regulation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.420.041RNA microarray19698090
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)17.62< 0.05RNA-seq23757392
Exp23757392cRattus norvegicus18kidneywholeDiabetes (diabetic nephropathy)5.92< 0.05RNA-seq23757392
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.251.48E-03RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.333.02E-03RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.090.007717RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.160.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium