CKDdb-logoCKDdb - Molecule ID A244A

geneBhlhe41, Bhlhb3, 37591
nameClass E basic helix-loop-helix protein 41
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BHE41_MOUSEQ99PV5ENSMUSG0000003025679362Mm.154529606200, 612975

Functions and classifications

GOC:nucleoplasm, C:transcriptional repressor complex, F:bHLH transcription factor binding, F:E-box binding, F:histone deacetylase binding, F:MRF binding, F:protein binding, F:protein heterodimerization activity, F:protein homodimerization activity, F:RNA polymerase II activating transcription factor binding, F:RNA polymerase II core promoter proximal region sequence-specific DNA binding, F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, F:sequence-specific DNA binding RNA polymerase II transcription factor activity, F:transcription corepressor activity, P:circadian regulation of gene expression, P:circadian rhythm, P:negative regulation of myotube differentiation, P:negative regulation of transcription by competitive promoter binding, P:negative regulation of transcription from RNA polymerase II promoter, P:negative regulation of transcription, DNA-templated, P:transcription from RNA polymerase II promoter, C:nucleus, F:DNA binding, P:transcription, DNA-templated, C:transcriptional repressor complex, F:transcription corepressor activity, P:negative regulation of transcription from RNA polymerase II promoter, C:nucleus, C:transcriptional repressor complex, F:DNA binding, F:transcription corepressor activity, P:negative regulation of transcription from RNA polymerase II promoter, P:transcription, DNA-templated
UniProtBiological rhythms, Complete proteome, DNA-binding, Nucleus, Reference proteome, Repressor, Transcription, Transcription regulation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)6.65< 0.05RNA microarray21752957
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.241.53E-21NGS, RNA-seq.22266139
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)2.80.000116RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium