CKDdb-logoCKDdb - Molecule ID A243A

geneBHLHE22, BHLHB5, TNRC20
nameBasic helix-loop-helix protein 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BHE22_HUMANQ8NFJ8ENSG0000018082827319Hs.388788613483

Functions and classifications

GOC:nucleus, F:chromatin binding, F:sequence-specific DNA binding RNA polymerase II transcription factor activity, P:anterior commissure morphogenesis, P:cerebral cortex regionalization, P:corpus callosum morphogenesis, P:corticospinal tract morphogenesis, P:negative regulation of transcription, DNA-templated, P:retinal bipolar neuron differentiation, P:negative regulation of transcription, DNA-dependent, P:retinal bipolar neuron differentiation, P:transcription, DNA-dependent"
UniProtComplete proteome, Nucleus, Polymorphism, Reference proteome, Repressor, Transcription, Transcription regulation
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.242.54E-03RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.442.49E-05RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.10.004272RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium