CKDdb-logoCKDdb - Molecule ID A240A

geneBCOR
nameBCL-6 corepressor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BCOR_HUMANQ6W2J9ENSP0000034592354880Hs.659681300166, 300485

Functions and classifications

GOC:nucleus, F:heat shock protein binding, F:transcription corepressor activity, F:transcription regulatory region DNA binding, P:heart development, P:histone H2A monoubiquitination, P:negative regulation of bone mineralization, P:negative regulation of histone H3-K36 methylation, P:negative regulation of histone H3-K4 methylation, P:negative regulation of tooth mineralization, P:negative regulation of transcription from RNA polymerase II promoter, P:odontogenesis, P:palate development, P:specification of axis polarity, P:transcription, DNA-templated, C:nucleus, P:transcription, DNA-dependent
UniProt3D-structure, Acetylation, Alternative splicing, ANK repeat, Chromatin regulator, Complete proteome, Disease mutation, Microphthalmia, Nucleus, Phosphoprotein, Reference proteome, Repeat, Repressor, Transcription, Transcription regulation
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20847290Homo sapiens30kidneyglomeruliGlomerulonephritis (FSGS + COLL)0.310.0995RNA microarray20847290
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.359.59E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium