CKDdb-logoCKDdb - Molecule ID A2396

geneACAP2, CENTB2
nameARF-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACAP2_HUMANQ15057ENSG0000011433123527Hs.593373607766

Functions and classifications

GOC:endosome membrane, F:ARF GTPase activator activity, F:zinc ion binding, P:cellular response to nerve growth factor stimulus, P:positive regulation of GTPase activity, P:protein localization to endosome, P:regulation of ARF GTPase activity, F:metal ion binding, F:phospholipid binding
UniProtANK repeat, Coiled coil, Complete proteome, Endosome, GTPase activation, Membrane, Metal-binding, Phosphoprotein, Reference proteome, Repeat, Zinc, Zinc-finger
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp25770168Homo sapiens17bloodmononuclear cellsGlomerulonephritis (IgA nephropathy) 5.660.002RNA microarray  25770168

Compile date 08-30-2016© iMODE-CKD consortium