CKDdb-logoCKDdb - Molecule ID A2383

geneARHGAP26, GRAF, OPHN1L
nameRHO GTPase-activating protein 26
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
RHG26_HUMANQ9UNA1ENSG0000014581923092Hs.654668605370, 607785

Functions and classifications

GOC:cytoskeleton, C:cytosol, C:focal adhesion, F:phospholipid binding, F:Rho GTPase activator activity, P:actin cytoskeleton organization, P:filopodium assembly, P:nervous system development, P:small GTPase mediated signal transduction, C:intracellular, P:signal transduction
UniProt3D-structure, Alternative splicing, Cell junction, Chromosomal rearrangement, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, GTPase activation, Proto-oncogene, Reference proteome, SH3 domain
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.270.00724RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.360.000000663RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)2.97< 0.05RNA microarray21752957
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.498.32E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium