CKDdb-logoCKDdb - Molecule ID A2376

geneARHGAP25
nameRho GTPase activating protein 25
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
RHG25_HUMANP42331ENSG000001632199938Hs.531807610587

Functions and classifications

GOC:cytosol, F:GTPase activator activity, P:positive regulation of GTPase activity, P:regulation of small GTPase mediated signal transduction, P:small GTPase mediated signal transduction, C:intracellular, P:signal transduction, F:phospholipid binding, F:GTP binding, F:GTPase activity, P:GTP catabolic process
UniProt3D-structure, Alternative splicing, Coiled coil, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteome
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.380.000179RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.053.23E-06RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.073.23E-06RNA microarray20019191
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.35< 0.05RNA microarray21752957
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.36< 0.05RNA microarray21752957
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.13< 0.05RNA-seq23757392
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.337.92E-04RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.160.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium