CKDdb-logoCKDdb - Molecule ID A2360

geneARHGAP1, CDC42GAP, RHOGAP1
nameRho-GTPase-activating protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
RHG01_HUMANQ07960ENSG00000175220392Hs.138860602732

Functions and classifications

GOC:cytosol, C:intracellular membrane-bounded organelle, C:plasma membrane, C:ruffle, F:Rac GTPase activator activity, F:Rho GTPase activator activity, F:SH3/SH2 adaptor activity, P:Rho protein signal transduction, C:intracellular, P:signal transduction, F:GTP binding
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, GTPase activation, Phosphoprotein, Polymorphism, Reference proteome, SH3-binding
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19139726Homo sapiens21kidneyproximal tubuleproteinuria (proteinuria)5.56< 0.05cDNA microarray19139726
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.330.00000037RNA microarray19698090
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.810.005325151LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.431.02E-05RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)8.957.44E-08RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)7.10.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium