CKDdb-logoCKDdb - Molecule ID A2355

geneArhgap24
nameRho GTPase-activating protein 24
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
RHG24_RATQ5U2Z7ENSRNOG00000002095305156Rn.24657610586

Functions and classifications

GOC:cell projection, C:cytoplasm, C:cytoskeleton, C:focal adhesion, C:plasma membrane, F:Rac GTPase activator activity, P:activation of Rac GTPase activity, P:angiogenesis, P:cell differentiation, P:negative regulation of Rac protein signal transduction, P:negative regulation of ruffle assembly, P:signal transduction, P:wound healing, spreading of epidermal cells, F:GTPase activator activity, F:phospholipid binding, P:positive regulation of GTPase activity
UniProtAlternative splicing, Angiogenesis, Cell junction, Cell projection, Coiled coil, Complete proteome, Cytoplasm, Cytoskeleton, Developmental protein, Differentiation, GTPase activation, Phosphoprotein, Reference proteome
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.473.23E-06RNA microarray20019191
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.230.000146RNA microarray23291264
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.450.0267RNA microarray23291264
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.441.40E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium