CKDdb-logoCKDdb - Molecule ID A2343

geneACTN3
nameAlpha-actinin 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACTN3_HUMANQ08043ENSG0000024874689Hs.654432102574

Functions and classifications

GOC:actin filament, C:cytosol, C:focal adhesion, C:pseudopodium, F:calcium ion binding, F:integrin binding, F:protein homodimerization activity, F:structural constituent of muscle, P:focal adhesion assembly, P:muscle filament sliding, P:regulation of apoptotic process, P:actin crosslink formation, P:actin filament bundle assembly
UniProt3D-structure, Actin-binding, Calcium, Complete proteome, Metal-binding, Polymorphism, Reference proteome, Repeat
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.290.000285RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium