CKDdb-logoCKDdb - Molecule ID A2271

geneANGPTL3, ANGPT5, UNQ153/PRO179
nameAngiopoietin-related protein 3 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANGL3_HUMANQ9Y5C1ENSP0000036017027329Hs.209153604774, 605019

Functions and classifications

GOC:cell surface, C:extracellular space, F:growth factor activity, F:phospholipase inhibitor activity, P:artery morphogenesis, P:cell-matrix adhesion, P:cholesterol homeostasis, P:cholesterol metabolic process, P:fatty acid metabolic process, P:glycerol metabolic process, P:integrin-mediated signaling pathway, P:lipid storage, P:negative regulation of lipoprotein lipase activity, P:negative regulation of phospholipase activity, P:phospholipid catabolic process, P:phospholipid homeostasis, P:positive regulation of angiogenesis, P:positive regulation of cell migration, P:positive regulation of lipid catabolic process, P:response to hormone, P:triglyceride homeostasis, F:enzyme inhibitor activity, F:cell surface binding, P:response to hormone stimulus, P:signal transduction
UniProtCoiled coil, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Polymorphism, Reference proteome, Secreted, Signal
PADBUK: unknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.397.27E-05RNA microarray20019191
Exp23757392bRattus norvegicus13kidneywholeDiabetes (diabetic nephropathy)3.2< 0.05RNA-seq23757392

Compile date 08-10-2018© iMODE-CKD consortium