CKDdb-logoCKDdb - Molecule ID A226F

geneAckr3, Cmkor1, Cxcr7
nameAtypical chemokine receptor 3
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ACKR3_MOUSEP56485ENSMUSG0000004433712778Mm.491219

Functions and classifications

GOC:cell surface, C:coated pit, C:early endosome, C:endosome, C:integral component of membrane, C:perinuclear region of cytoplasm, C:plasma membrane, C:recycling endosome, F:C-X-C chemokine binding, F:C-X-C chemokine receptor activity, F:coreceptor activity, F:scavenger receptor activity, P:angiogenesis, P:cell adhesion, P:chemotaxis, P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage, P:positive regulation of ERK1 and ERK2 cascade, P:receptor internalization, P:vasculogenesis, C:integral to membrane, P:multicellular organismal development, P:negative regulation of apoptotic process
UniProtCell adhesion, Cell membrane, Complete proteome, Cytoplasm, Developmental protein, Disulfide bond, Endosome, G-protein coupled receptor, Glycoprotein, Membrane, Phosphoprotein, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix, Ubl conjugation
PADBreceptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp17327501aMus musculus6kidneywholeIAKI (Ischemic acute kidney injury) 31.34< 0.05RNA microarray  17327501
Exp17327501bMus musculus6kidneywholeIAKI (Ischemic acute kidney injury) 23.26< 0.05RNA microarray  17327501

Compile date 08-30-2016© iMODE-CKD consortium