CKDdb-logoCKDdb - Molecule ID A2226

geneBPTF, FAC1, FALZ
nameNucleosome-remodeling factor subunit BPTF
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BPTF_HUMANQ12830ENSP000003072082186Hs.444200601819

Functions and classifications

GOC:cytoplasm, C:NURF complex, F:sequence-specific DNA binding, F:transcription factor binding, F:zinc ion binding, P:anterior/posterior pattern specification, P:ATP catabolic process, P:brain development, P:chromatin remodeling, P:embryonic placenta development, P:endoderm development, P:negative regulation of transcription from RNA polymerase II promoter, P:positive regulation of transcription, DNA-templated, P:transcription, DNA-templated, F:metal ion binding, P:positive regulation of transcription, DNA-dependent, P:transcription, DNA-dependent, C:nucleus
UniProt3D-structure, Acetylation, Alternative splicing, Bromodomain, Chromatin regulator, Coiled coil, Complete proteome, Cytoplasm, Metal-binding, Nucleus, Phosphoprotein, Reference proteome, Repeat, Transcription, Transcription regulation, Zinc, Zinc-finger
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.343.23E-06RNA microarray20019191
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.040.045324529LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.423.83E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium