CKDdb-logoCKDdb - Molecule ID A217F

geneAcer2, Asah3l
nameAlkaline ceramidase 2
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ACER2_MOUSEQ8VD53ENSMUSG00000038007230379Mm.45019

Functions and classifications

GOC:integral component of Golgi membrane, F:dihydroceramidase activity, P:activation of cysteine-type endopeptidase activity involved in apoptotic process, P:cellular response to drug, P:ceramide metabolic process, P:negative regulation of cell adhesion mediated by integrin, P:negative regulation of cell-matrix adhesion, P:negative regulation of protein glycosylation in Golgi, P:positive regulation of cell death, P:positive regulation of cell proliferation, P:response to retinoic acid, P:sphingosine biosynthetic process,
UniProtAlternative splicing, Complete proteome, Glycoprotein, Golgi apparatus, Hydrolase, Lipid metabolism, Membrane, Reference proteome, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI) 2.790.00255RNA microarray  24569379

Compile date 08-30-2016© iMODE-CKD consortium