CKDdb-logoCKDdb - Molecule ID A216F

geneAcer1, Asah3
nameAlkaline ceramidase 1
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ACER1_MOUSEQ8R4X1ENSMUSG00000045019171168Mm.218784

Functions and classifications

GOC:endoplasmic reticulum, C:endoplasmic reticulum membrane, C:integral component of membrane, F:ceramidase activity, F:dihydroceramidase activity, P:cellular response to calcium ion, P:ceramide catabolic process, P:keratinocyte differentiation, P:regulation of lipid metabolic process, P:response to alkalinity, P:sphingolipid metabolic process, P:sphingosine biosynthetic process, C:integral to membrane
UniProtComplete proteome, Endoplasmic reticulum, Hydrolase, Lipid metabolism, Membrane, Reference proteome, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease) 0.390cDNA microarray  19099603

Compile date 08-30-2016© iMODE-CKD consortium