CKDdb-logoCKDdb - Molecule ID A2149

geneASCC3, HELIC1, RNAH
nameActivating signal cointegrator 1 complex subunit 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ASCC3_HUMANQ8N3C0ENSP0000035813910973Hs.486031614217

Functions and classifications

GOC:cytoplasm, C:nucleus, F:ATP binding, F:ATP-dependent 3'-5' DNA helicase activity, F:nucleic acid binding, P:cell proliferation, P:DNA dealkylation involved in DNA repair, P:regulation of transcription, DNA-templated, P:transcription, DNA-templated, C:Golgi apparatus, F:ATP-dependent helicase activity, P:ATP catabolic process, P:regulation of transcription, DNA-dependent, P:transcription, DNA-dependent
UniProtAcetylation, Alternative splicing, ATP-binding, Coiled coil, Complete proteome, Cytoplasm, Direct protein sequencing, DNA damage, DNA repair, Helicase, Hydrolase, Nucleotide-binding, Nucleus, Polymorphism, Reference proteome, Repeat, Transcription, Transcription regulation
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)2.99< 0.05RNA microarray21752957
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.497.02E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium