CKDdb-logoCKDdb - Molecule ID A209F

geneABHD5, NCIE2, CGI-58
name1-acylglycerol-3-phosphate O-acyltransferase ABHD5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABHD5_HUMANQ8WTS1ENSG0000001119851099Hs.19385275630, 604780

Functions and classifications

GOC:cytosol, C:lipid particle, F:1-acylglycerol-3-phosphate O-acyltransferase activity, F:lysophosphatidic acid acyltransferase activity, P:cell differentiation, P:fatty acid metabolic process, P:negative regulation of sequestering of triglyceride, P:phosphatidic acid biosynthetic process, P:positive regulation of lipoprotein lipase activity, P:positive regulation of triglyceride catabolic process, P:small molecule metabolic process, P:triglyceride catabolic process, P:lipid metabolic process, F:hydrolase activity, P:metabolic process, F:peptidase activity, P:proteolysis
UniProtAcetylation, Acyltransferase, Cataract, Complete proteome, Cytoplasm, Deafness, Differentiation, Disease mutation, Fatty acid metabolism, Ichthyosis, Lipid biosynthesis, Lipid droplet, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism, Reference proteome, Transferase, Hydrolase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.170.000516RNA microarray  19698090

Compile date 08-30-2016© iMODE-CKD consortium