CKDdb-logoCKDdb - Molecule ID A207A

geneAFF1, AF-4, MLLT2
nameAF4/FMR2 family member 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AFF1_HUMANP51825ENSG000001724934299Hs.480190159557

Functions and classifications

GOC:nucleus, F:sequence-specific DNA binding transcription factor activity, P:positive regulation of transcription, DNA-templated, C:nucleus, P:positive regulation of transcription, DNA-dependent
UniProt3D-structure, Acetylation, Alternative splicing, Chromosomal rearrangement, Complete proteome, Nucleus, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteome
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)0.370.0023908RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.197.49E-08RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.270.00188RNA microarray19698090
Exp19836472Mus musculus kidneytubule cellsDiabetes (Diabetic Nephropathy)0.16 LC-MS/MS19836472
Exp20485333Homo sapiens20bloodwholeGlomerulonephritis (IgA nephropathy)2.210.005932RNA microarray20485333
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.431.19E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium