CKDdb-logoCKDdb - Molecule ID A2028

geneARID4A, RBBP1, RBP1
nameRetinoblastoma-binding protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARI4A_HUMANP29374ENSG000000322195926Hs.161000180201

Functions and classifications

GOC:transcriptional repressor complex, F:DNA binding, F:sequence-specific DNA binding transcription factor activity, P:erythrocyte development, P:histone H3-K4 trimethylation, P:histone H3-K9 trimethylation, P:histone H4-K20 trimethylation, P:negative regulation of transcription, DNA-templated, P:regulation of gene expression by genetic imprinting, P:transcription from RNA polymerase II promoter, C:nucleus, P:negative regulation of transcription, DNA-dependent, C:intracellular
UniProt3D-structure, Alternative splicing, Complete proteome, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Transcription, Transcription regulation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)0.440.0194152RNA microarray19698090
Exp20485333Homo sapiens20bloodwholeGlomerulonephritis (IgA nephropathy)2.040.005089RNA microarray20485333
Exp20847290Homo sapiens30kidneyglomeruliGlomerulonephritis (FSGS + COLL)2.060.0601RNA microarray20847290

Compile date 08-10-2018© iMODE-CKD consortium