CKDdb-logoCKDdb - Molecule ID A1969

geneGSTO1, GSTTLP28
nameGlutathione transferase omega 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
GSTO1_HUMANP78417ENSG000001488349446Hs.190028605482

Functions and classifications

GOC:cytosol, F:glutathione dehydrogenase (ascorbate) activity, F:glutathione transferase activity, F:methylarsonate reductase activity, P:cellular response to arsenic-containing substance, P:glutathione derivative biosynthetic process, P:L-ascorbic acid metabolic process, P:negative regulation of ryanodine-sensitive calcium-release channel activity, P:positive regulation of ryanodine-sensitive calcium-release channel activity, P:positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion, P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, P:xenobiotic catabolic process, C:cytoplasm, P:L-ascorbic acid biosynthetic process, F:transferase activity
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, Direct protein sequencing, Oxidoreductase, Polymorphism, Reference proteome, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.87< 0.05cDNA microarray17003339
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.87< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.73< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.73< 0.05cDNA microarray17003339
Exp19369687Mus musculus kidneyproximal tubule cellsCyclosporine_A_induced (Ciclosporine A in vitro model)0.53< 0.04MALDI TOF/TOF19369687
Exp19369687Mus musculus kidneyproximal tubule cellsCyclosporine_A_induced (Ciclosporine A in vitro model)2.45< 0.05MALDI TOF/TOF19369687
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.220.00000688RNA microarray19698090
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.66 nLC-ESI-UHR-QToF-MS/MS23344851

Compile date 08-10-2018© iMODE-CKD consortium