CKDdb-logoCKDdb - Molecule ID A195A

geneAZGP1, ZAG, ZNGP1
nameZinc-alpha-2-glycoprotein precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ZA2G_HUMANP25311ENSG00000160862563Hs.546239194460

Functions and classifications

GOC:extracellular space, C:MHC class I protein complex, C:plasma membrane, F:antigen binding, F:peptide antigen binding, F:protein transmembrane transporter activity, F:ribonuclease activity, P:antigen processing and presentation, P:antigen processing and presentation of peptide antigen via MHC class I, P:cell adhesion, P:immune response, P:negative regulation of cell proliferation, P:positive regulation of T cell mediated cytotoxicity, C:membrane, C:extracellular region, F:fatty acid binding, P:lipid catabolic process
UniProt3D-structure, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Pyrrolidone carboxylic acid, Reference proteome, Secreted, Signal
PADBtransmembrane

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionValidationPubMed/DOI
Exp16372274Homo sapiens25urinewholeGlomerulonephritis (IgA nephropathy)27.5< 0.05MALDI-TOF-MS 16372274
Exp16372274Homo sapiens25urinewholeGlomerulonephritis (IgA nephropathy)52< 0.05MALDI-TOF-MS 16372274
Exp17242005Homo sapiens27urinewholeGlomerulonephritis (IgA nephropathy)4.2 LC-MS/MS 17242005
Exp17301227Homo sapiens13bloodserumFabry (6 months of ERT) 0.3125nanoLC-ESI-MS/MS 17301227
Exp17327332aHomo sapiens42urinewholeDiabetes (Diabetic Nephropathy)5.86< 0.05LC-MS/MS 17327332
Exp17327332bHomo sapiens42urinewholeDiabetes (Diabetic Nephropathy)5.97< 0.05LC-MS/MS 17327332
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.290.00145RNA microarray 19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.323.59E-05RNA microarray 20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.341.98E-05RNA microarray 20019191
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)up MS/MS, LTQ LX linear ion trap 20093355
Exp20134395Homo sapiens9urinewholeFibrosis (Interstitial fibrosis and tubular atrophy)2.790.046MALDI-TOF-MS, LTQ linear ion trap, capLC-ESI-ITMS/MS 20134395
Exp20134395Homo sapiens9urinewholeFibrosis (Interstitial fibrosis and tubular atrophy)2.890.037MALDI-TOF-MS, LTQ linear ion trap, capLC-ESI-ITMS/MS 20134395
Exp20411046Homo sapiens5kidneycyst fluidPolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease) < 0.001LC-MS/MS 20411046
Exp20812764Homo sapiens13bloodplasmaTransplantation (Acute Renal Allograft Rejection)8.550.0055LC-MS/MS 20812764
Exp22498882Homo sapiens10urinewholeGlomerulonephritis (lupus nephritis)3.310.001ESI-Q-TOF MS/MSELISA22498882
Exp22498882Homo sapiens10urinewholeGlomerulonephritis (lupus nephritis)5.49< 0.0001ESI-Q-TOF MS/MSELISA22498882
Exp22498882Homo sapiens10urinewholeGlomerulonephritis (lupus nephritis)6.710.002ESI-Q-TOF MS/MSELISA22498882
Exp22536212Homo sapiens86urinewholeDiabetes (type 2 diabetic nephropathy)1.480hybrid quadrupole-TOF, LC-MS/MS 22536212
Exp22536212Homo sapiens86urinewholeDiabetes (type 2 diabetic nephropathy)1.80hybrid quadrupole-TOF, LC-MS/MS 22536212
Exp23078846Homo sapiens12kidneyperitoneal dialysateDialysis (Peritonitis)down< 0.05RP-nano-HPLC-ESI-MS/MSwestern blot, ELISA23078846
Exp23143504Homo sapiens urinewholeAKI (AKI)4.110.03LC-MS/MS 23143504
Exp23205849Homo sapiens40bloodplasmaGlomerulonephritis (FSGS)up< 0.0001MALDI-TOF 23205849
Exp24096133aHomo sapiens10urine>10kDaDiabetes (type 1 diabetes without retinopathy or nephropathy)0.34 1DE, MALDI 24096133
Exp24096133dHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy vs type 1 diabetes without retinopathy or nephropathy)5.23 1DE, MALDI 24096133
Exp24096133eHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes without retinopathy or nephropathy)2.11 1DE, MALDI 24096133
Exp24096133fHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes with retinopathy)0.4 1DE, MALDI 24096133
Exp25578432aHomo sapiens60urinesupernatantDiabetes (type 2 diabetes without nephropathy)1.081LC-MS/MS 25578432
Exp25578432bHomo sapiens42urinesupernatantDiabetes (type 2 diabetes with retinopathy)1.210.03LC-MS/MS 25578432
Exp25578432cHomo sapiens51urinesupernatantDiabetes (diabetes with overt diabetic nephropathy)1.021LC-MS/MS 25578432
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)20.670.013999RNA microarray 26317775

Compile date 08-10-2018© iMODE-CKD consortium