CKDdb-logoCKDdb - Molecule ID A1935

geneCADM1, IGSF4, IGSF4A
nameCell adhesion molecule 1 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CADM1_HUMANQ9BY67ENSG0000018298523705Hs.370510605686

Functions and classifications

GOC:axon, C:basolateral plasma membrane, C:cell-cell junction, C:dendrite, C:integral component of membrane, C:synaptic vesicle, F:PDZ domain binding, F:protein C-terminus binding, F:protein homodimerization activity, F:receptor binding, P:adherens junction organization, P:apoptotic process, P:bone development, P:brain development, P:calcium-independent cell-cell adhesion, P:cell differentiation, P:cell junction assembly, P:cell recognition, P:detection of stimulus, P:heterophilic cell-cell adhesion, P:homophilic cell adhesion, P:immune system process, P:liver development, P:positive regulation of cytokine secretion, P:spermatogenesis, P:susceptibility to natural killer cell mediated cytotoxicity, P:synapse assembly, P:unidimensional cell growth, C:integral to membrane
UniProt3D-structure, Alternative splicing, Apoptosis, Cell adhesion, Cell junction, Cell membrane, Complete proteome, Developmental protein, Differentiation, Disulfide bond, Glycoprotein, Immunity, Immunoglobulin domain, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Signal, Spermatogenesis, Synapse, Transmembrane, Transmembrane helix, Tumor suppressor
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18354378Homo sapiens8kidneyepithelial cellsureteral_obstruction (unilateral ureteral obstruction)0.224 +/- 1.248< 0.05RNA microarray18354378
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection)0.2 LC-MS/MS20543976
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection)0.2 LC-MS/MS20543976
Exp22536212Homo sapiens86urinewholeDiabetes (type 2 diabetic nephropathy)0.710.01hybrid quadrupole-TOF, LC-MS/MS22536212
Exp22891811aHomo sapiens10urinewholeureteral_obstruction (congenital bilateral hydronephrosis)1.72 +/- 0.002 < 0.05LC-MS/MS22891811
Exp22891811bHomo sapiens10urinewholeureteral_obstruction (congenital bilateral hydronephrosis)1.43 +/- 0.013< 0.05LC-MS/MS22891811
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)0.680.01829LC-MS/MS23228063
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)4.280.0176402RNA microarray23935909

Compile date 08-10-2018© iMODE-CKD consortium