CKDdb-logoCKDdb - Molecule ID A1924

geneALDOB, ALDB
nameFructose-bisphosphate aldolase B
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALDOB_HUMANP05062ENSG00000136872229Hs.530274229600, 612724

Functions and classifications

GOC:centriolar satellite, C:cytosol, F:ATPase binding, F:cytoskeletal protein binding, F:fructose binding, F:fructose-bisphosphate aldolase activity, P:fructose 1,6-bisphosphate metabolic process, P:fructose catabolic process, P:gluconeogenesis, P:glycolysis, P:NADH oxidation, P:positive regulation of ATPase activity, P:vacuolar proton-transporting V-type ATPase complex assembly, C:lysosome, C:nucleus, C:perinuclear region of cytoplasm, C:plasma membrane, C:rough endoplasmic reticulum membrane, C:smooth endoplasmic reticulum membrane, F:phosphatidylcholine binding, P:cellular response to extracellular stimulus, P:cellular response to insulin stimulus, P:liver development, P:response to amino acid stimulus, P:response to cAMP, P:response to copper ion, P:response to drug, P:response to fructose stimulus, P:response to glucocorticoid stimulus, P:response to interleukin-6, P:response to starvation, P:response to zinc ion
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Disease mutation, Glycolysis, Lyase, Phosphoprotein, Polymorphism, Reference proteome, Schiff base
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.230.02cDNA microarray19099603
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.240.02cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.310.01cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.310.01cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.160.0000127RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.340.0105RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.340.0144RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.460.00322RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.262.62E-05RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.313.59E-05RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.428.81E-05RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.470.000158024RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.490.000113537RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.514.60E-05RNA microarray20019191
Exp20959534Mus musculus kidneywholeDiabetes (type 2 diabetes)2.2< 0.05MALDI-TOF-MS20959534
Exp21595033bHomo sapiens14urineexosomesGlomerulonephritis (basement membrane nephropathy)0.240.00341LC-MS/MS21595033
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.04< 0.05RNA microarray21752957
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.250.000564RNA microarray23291264
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.370.0049RNA microarray23291264
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.66 nLC-ESI-UHR-QToF-MS/MS23344851
Exp24497609Rattus norvegicus kidneyglomeruliPuromycin_induced (Puromycin nephropathy model)0.62< 0.05LC-MS/MS24497609
Exp25279147Homo sapiens12kidneybiopsy sectionGlomerulonephritis (IgA nephropathy)0.25< 0.05MALDI TOF/TOF25279147

Compile date 08-10-2018© iMODE-CKD consortium