CKDdb-logoCKDdb - Molecule ID A1923

geneALDOA, ALDA
nameFructose-bisphosphate aldolase A
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALDOA_HUMANP04075ENSP00000336927226Hs.513490103850, 611881

Functions and classifications

GOC:actin cytoskeleton, C:cytosol, C:extracellular vesicular exosome, C:I band, C:platelet alpha granule lumen, F:actin binding, F:fructose binding, F:fructose-bisphosphate aldolase activity, F:identical protein binding, F:tubulin binding, P:actin filament organization, P:ATP biosynthetic process, P:fructose 1,6-bisphosphate metabolic process, P:fructose metabolic process, P:gluconeogenesis, P:glycolysis, P:muscle cell cellular homeostasis, P:platelet activation, P:platelet degranulation, P:protein homotetramerization, P:regulation of cell shape, P:striated muscle contraction, P:muscle cell homeostasis
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Direct protein sequencing, Disease mutation, Glycogen storage disease, Glycolysis, Hereditary hemolytic anemia, Lyase, Phosphoprotein, Polymorphism, Reference proteome, Schiff base
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17183245Homo sapiens24kidneyproximal tubuleproteinuria (proteinuric nephropathies)5.94< 0.05cDNA microarrays17183245
Exp18850734Canis lupus familiaris kidneydistal renal tubular cellskidney_calculi (Calcium oxalate monohydrate in vitro model)0.19<0.001Q-TOF MS/MS18850734
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)up MS/MS, LTQ LX linear ion trap20093355
Exp25279147Homo sapiens12kidneybiopsy sectionGlomerulonephritis (IgA nephropathy)2.38< 0.05MALDI TOF/TOF25279147
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.472.09E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium