CKDdb-logoCKDdb - Molecule ID A1876

geneABCC9, SUR2
nameSulfonylurea receptor 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCC9_HUMANO60706ENSG0000006943110060Hs.732701239850, 601439, 608569, 614050

Functions and classifications

GOC:ATP-sensitive potassium channel complex, C:sarcolemma, C:sarcomere, C:voltage-gated potassium channel complex, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, F:potassium channel activity, F:potassium channel regulator activity, F:sulfonylurea receptor activity, F:transporter activity, P:ATP catabolic process, P:defense response to virus, P:potassium ion import, P:synaptic transmission, C:integral component of membrane, P:potassium ion transport, P:signal transduction, C:membrane, P:signal transduction, F:ATPase activity, C:integral to membrane, P:potassium ion transport, C:plasma membrane
UniProtAlternative splicing, ATP-binding, Atrial fibrillation, Cardiomyopathy, Complete proteome, Disease mutation, Glycoprotein, Membrane, Nucleotide-binding, Polymorphism, Receptor, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.20.0000787RNA microarray  19698090
Exp21411733aMus musculus13macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis) 0.460.002cDNA microarray  21411733
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis) 2.070.009cDNA microarray  21411733
Exp24172336Mus musculus6kidneycortexAKI (AKI) 0.910.011083231LC-MS/MS  24172336
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 0.160.013999RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium