CKDdb-logoCKDdb - Molecule ID A1858

geneARHGAP35, GRF1, GRLF1
nameGlucocorticoid receptor DNA binding factor 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
RHG35_HUMANQ9NRY4ENSG000001600072909Hs.509447605277

Functions and classifications

GOC:actin cytoskeleton, C:cytosol, C:nucleus, F:DNA binding, F:GTP binding, F:Rho GTPase activator activity, F:transcription corepressor activity, P:axon guidance, P:camera-type eye development, P:forebrain development, P:negative regulation of transcription, DNA-templated, P:negative regulation of vascular permeability, P:neural tube closure, P:regulation of cell shape, P:small GTPase mediated signal transduction, P:transcription, DNA-templated, C:intracellular, P:signal transduction, P:negative regulation of transcription, DNA-dependent, P:transcription, DNA-dependent
UniProt3D-structure, Complete proteome, Cytoplasm, DNA-binding, GTPase activation, Nucleus, Phosphoprotein, Reference proteome, Repeat, Repressor, Transcription, Transcription regulation, Tumor suppressor, Receptor
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.490.014RNA microarray19698090
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)6.810.006399RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium