CKDdb-logoCKDdb - Molecule ID A1852

geneCAMK2G, CAMK, CAMK-II
nameCalcium/calmodulin-dependent protein kinase type II gamma chain
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KCC2G_HUMANQ13555ENSG00000148660818Hs.523045602123

Functions and classifications

GOC:calcium- and calmodulin-dependent protein kinase complex, C:cytosol, C:endocytic vesicle membrane, C:nucleoplasm, C:plasma membrane, C:sarcoplasmic reticulum membrane, F:ATP binding, F:calcium-dependent protein serine/threonine phosphatase activity, F:calmodulin binding, F:calmodulin-dependent protein kinase activity, P:calcium ion transport, P:cell differentiation, P:G1/S transition of mitotic cell cycle, P:insulin secretion, P:interferon-gamma-mediated signaling pathway, P:nervous system development, P:protein autophosphorylation, P:protein phosphorylation, P:regulation of calcium ion transport, P:regulation of relaxation of cardiac muscle, P:regulation of skeletal muscle adaptation, P:synaptic transmission, F:protein serine/threonine kinase activity, P:response to hypoxia, P:response to oxidative stress, F:protein kinase activity
UniProt3D-structure, Alternative splicing, ATP-binding, Calmodulin-binding, Complete proteome, Developmental protein, Differentiation, Kinase, Membrane, Neurogenesis, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Sarcoplasmic reticulum, Serine/threonine-protein kinase, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.220.00000176RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.420.00000387RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.430.00000324RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.34< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium