CKDdb-logoCKDdb - Molecule ID A1851

geneCAMK2B, CAM2, CAMKB
nameCalcium/calmodulin-dependent protein kinase IIB
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KCC2B_HUMANQ13554ENSG00000058404816Hs.351887607707

Functions and classifications

GOC:cytosol, C:endocytic vesicle membrane, C:microtubule organizing center, C:nucleoplasm, C:plasma membrane, C:sarcoplasmic reticulum membrane, C:spindle midzone, F:ATP binding, F:calmodulin-dependent protein kinase activity, P:activation of meiosis involved in egg activation, P:calcium ion transport, P:G1/S transition of mitotic cell cycle, P:inhibitory G-protein coupled receptor phosphorylation, P:interferon-gamma-mediated signaling pathway, P:neuromuscular process controlling balance, P:peptidyl-serine phosphorylation, P:positive regulation of apoptotic signaling pathway, P:positive regulation of dendritic spine morphogenesis, P:positive regulation of neuron projection development, P:positive regulation of synapse maturation, P:protein autophosphorylation, P:regulation of calcium ion transport, P:regulation of long-term neuronal synaptic plasticity, P:regulation of skeletal muscle adaptation, P:regulation of synapse structural plasticity, P:regulation of synaptic transmission, cholinergic, P:response to cadmium ion, F:protein serine/threonine kinase activity, F:protein kinase activity
UniProt3D-structure, Actin-binding, Alternative splicing, ATP-binding, Calmodulin-binding, Complete proteome, Cytoplasm, Cytoskeleton, Developmental protein, Differentiation, Kinase, Membrane, Neurogenesis, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Sarcoplasmic reticulum, Serine/threonine-protein kinase, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.190.000278RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.250.000000173RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.410.0155RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.490.0103RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium