CKDdb-logoCKDdb - Molecule ID A1819

geneB2m
nameBeta-2-microglobulin
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
B2MG_MOUSEP01887ENSMUSG0000006080212010Mm.163109700, 241600

Functions and classifications

GOC:external side of plasma membrane, C:extracellular space, C:MHC class I protein complex, C:phagocytic vesicle membrane, F:protein binding, P:antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent, P:antigen processing and presentation of peptide antigen via MHC class I, P:cellular defense response, P:positive regulation of T cell mediated cytotoxicity, P:protein refolding, P:response to cadmium ion, P:response to drug, P:response to molecule of bacterial origin, P:T cell differentiation in thymus, C:extracellular region, P:immune response
UniProt3D-structure, Complete proteome, Direct protein sequencing, Disulfide bond, Immunity, Immunoglobulin domain, MHC I, Polymorphism, Reference proteome, Secreted, Signal
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp15760396Homo sapiens urinewholeTransplantation (acute renal allograft injury)up SELDI (H4 chip), MALDI15760396
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)3.990.05RNA microarray17579666
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)4.010.05RNA microarray17579666
Exp18187931aMus musculus20kidneyglomeruliGlomerulonephritis (lupus nephritis)2.8< 0.05RNA microarray18187931
Exp18187931bMus musculus18kidneyglomeruliGlomerulonephritis (lupus nephritis)2.2< 0.05RNA microarray18187931
Exp18440303Rattus norvegicus20urineglycoproteinsGlomerulonephritis (adriamycin nephropathy and Thy1.1 induced glomerulonephritis)3.27 LC-MS/MS18440303
Exp20134395Homo sapiens9urinewholeFibrosis (Interstitial fibrosis and tubular atrophy)6.680.046MALDI-TOF-MS, LTQ linear ion trap, capLC-ESI-ITMS/MS20134395
Exp20411046Homo sapiens5kidneycyst fluidPolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease) < 0.001LC-MS/MS20411046
Exp20411046Homo sapiens5kidneycyst fluidPolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease) < 0.001LC-MS/MS20411046
Exp20639044aHomo sapiens46urinewholeureteral_obstruction (unilateral uteropelvic junction obstruction)4.87< 0.05LC-MS/MS20639044
Exp20639044bHomo sapiens46urinewholeureteral_obstruction (unilateral uteropelvic junction obstruction)19.47< 0.05LC-MS/MS20639044
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)37.86< 0.05RNA microarray21752957
Exp22498882Homo sapiens10urinewholeGlomerulonephritis (lupus nephritis)6.20.022ESI-Q-TOF MS/MS22498882
Exp22536212Homo sapiens86urinewholeDiabetes (type 2 diabetic nephropathy)1.480hybrid quadrupole-TOF, LC-MS/MS22536212
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)3.690.00003LC-MS/MS23228063
Exp23577616Homo sapiens urinewholeGlomerulonephritis (IgA nephropathy)0.820.001MALDI-TOF-MS23577616
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.018792802LC-MS/MS24172336
Exp24339887Homo sapiens13urinewholeGlomerulonephritis (IgA nephropathy)31< 0.05GeLC-MS/MS24339887
Exp25032130Homo sapiens11urinewholeGlomerulonephritis (focal segmental glomerulosclerosis)4.98 nano-flow LC-MS/MS25032130
Exp25150443aHomo sapiens24urinesupernatantNephrotic_Syndrome (paediatric idiopathic nephrotic syndrome)2.89.00E-07LC-MS25150443
Exp25279147Homo sapiens12kidneybiopsy sectionGlomerulonephritis (IgA nephropathy)2.99< 0.05MALDI TOF/TOF25279147
Exp25666440Homo sapiens23urinesupernatantFabry (naive Fabry patients)0.470.000036nanoLC-ESI-MS/MS25666440
Exp25667632Homo sapiens10kidneybiopsy sectionGlomerulonephritis (membranous nephropathy)1.56< 0.05MALDI-TOF/TOF25667632
Exp25667632Homo sapiens10kidneybiopsy sectionGlomerulonephritis (membranous nephropathy)1.56< 0.05MALDI-TOF/TOF25667632

Compile date 08-10-2018© iMODE-CKD consortium