CKDdb-logoCKDdb - Molecule ID A1788

geneACKR4, CCRL1, CCBP2
nameAtypical chemokine receptor 4
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACKR4_HUMANQ9NPB9ENSP0000024988751554Hs.310512606065

Functions and classifications

GOC:early endosome, C:integral component of plasma membrane, C:recycling endosome, F:chemokine receptor activity, F:scavenger receptor activity, P:chemotaxis, P:immune response, P:receptor-mediated endocytosis, C:integral component of membrane, P:chemokine-mediated signaling pathway, C:integral to plasma membrane, F:C-C chemokine receptor activity, C:integral to membrane
UniProtCell membrane, Complete proteome, Disulfide bond, Endosome, G-protein coupled receptor, Glycoprotein, Membrane, Phosphoprotein, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease) 3.51< 0.05RNA microarray  21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease) 3.42< 0.05RNA microarray  21752957

Compile date 08-30-2016© iMODE-CKD consortium