CKDdb-logoCKDdb - Molecule ID A1735

geneC5AR2, GPR77, C5L2
nameC5a anaphylatoxin chemotactic receptor C5L2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
C5AR2_HUMANQ9P296ENSG0000013483027202Hs.534412609949

Functions and classifications

GOC:apical part of cell, C:basal plasma membrane, C:integral component of membrane, F:C5a anaphylatoxin receptor activity, F:N-formyl peptide receptor activity, P:chemotaxis, P:negative regulation of interleukin-6 secretion, P:negative regulation of neutrophil chemotaxis, P:negative regulation of tumor necrosis factor production, P:regulation of interleukin-8 secretion, C:integral to membrane, C:plasma membrane
UniProtCell membrane, Complete proteome, Disulfide bond, G-protein coupled receptor, Glycoprotein, Membrane, Polymorphism, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix
PADBreceptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.210.000991RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium