CKDdb-logoCKDdb - Molecule ID A1722

geneAPLP2, APPL2, HSD-2
nameAmyloid-like protein 2 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APLP2_HUMANQ06481ENSG00000084234334Hs.370247104776

Functions and classifications

GOC:integral component of membrane, C:nucleus, C:plasma membrane, F:DNA binding, F:heparin binding, F:serine-type endopeptidase inhibitor activity, F:transition metal ion binding, P:cellular copper ion homeostasis, P:cholesterol metabolic process, P:embryo development, P:extracellular matrix organization, P:forebrain development, P:G-protein coupled receptor signaling pathway, P:locomotory behavior, P:mating behavior, P:midbrain development, P:negative regulation of endopeptidase activity, P:neuromuscular process controlling balance, P:regulation of epidermal growth factor-activated receptor activity, P:regulation of protein binding, P:suckling behavior, C:integral to membrane
UniProtAlternative splicing, Cell membrane, Complete proteome, Disulfide bond, DNA-binding, Glycoprotein, Membrane, Nucleus, Polymorphism, Protease inhibitor, Reference proteome, Serine protease inhibitor, Signal, Transmembrane, Transmembrane helix
PADBinhibitor (protease, kinase, other enzymes, pathways)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.470.00000407RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)20.0000371RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)3.060.000000106RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)3.551.31E-08RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium