CKDdb-logoCKDdb - Molecule ID A1721

geneAPLP1
nameAmyloid-like protein 1 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APLP1_HUMANP51693ENSG00000105290333Hs.74565104775

Functions and classifications

GOC:basement membrane, C:Golgi apparatus, C:integral component of membrane, C:perinuclear region of cytoplasm, C:plasma membrane, F:heparin binding, F:transition metal ion binding, P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, P:apoptotic process, P:cell adhesion, P:cellular response to norepinephrine stimulus, P:endocytosis, P:extracellular matrix organization, P:forebrain development, P:mRNA polyadenylation, P:negative regulation of cAMP biosynthetic process, P:nervous system development, P:organ morphogenesis, P:regulation of translation, C:membrane, C:integral to membrane
UniProt3D-structure, Alternative splicing, Apoptosis, Cell adhesion, Cell membrane, Complete proteome, Copper, Cytoplasm, Endocytosis, Glycoprotein, Heparin-binding, Membrane, Metal-binding, Neurodegeneration, Reference proteome, Signal, Transmembrane, Transmembrane helix, Zinc
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.420.00145RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.35< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.29< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium