CKDdb-logoCKDdb - Molecule ID A1716

geneANAPC10, APC10
nameAnaphase promoting complex subunit 10
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APC10_HUMANQ9UM13ENSG0000016416210393Hs.480876613745

Functions and classifications

GOC:anaphase-promoting complex, C:cytosol, C:nucleoplasm, F:ubiquitin-protein ligase activity, P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, P:G2/M transition of mitotic cell cycle, P:mitosis, P:mitotic anaphase, P:mitotic spindle assembly checkpoint, P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:protein K11-linked ubiquitination, C:cytoplasm, P:cell division, P:mitotic cell cycle spindle assembly checkpoint
UniProt3D-structure, Acetylation, Cell cycle, Cell division, Complete proteome, Mitosis, Polymorphism, Reference proteome, Ubl conjugation pathway
PADBcell cycle (turnover, mitosis, meiosis)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)4.030.0000176RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.033.23E-06RNA microarray20019191
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.31< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium