CKDdb-logoCKDdb - Molecule ID A1713

geneLpl
nameLipoprotein lipase
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
LIPL_MOUSEP11152ENSMUSG0000001556816956Mm.1514238600, 609708

Functions and classifications

GOC:anchored component of membrane, C:cell surface, C:chylomicron, C:extracellular matrix, C:extracellular space, C:plasma membrane, C:very-low-density lipoprotein particle, F:heparin binding, F:lipoprotein lipase activity, F:protein binding, F:triglyceride binding, F:triglyceride lipase activity, P:positive regulation of cholesterol storage, P:positive regulation of macrophage derived foam cell differentiation, P:positive regulation of sequestering of triglyceride, P:response to cold, P:response to drug, P:triglyceride biosynthetic process, P:triglyceride catabolic process, P:triglyceride homeostasis, C:extracellular region, F:lipoprotein lipase activity, F:protein binding, P:lipid metabolic process, C:extracellular region, F:lipoprotein lipase activity, F:protein binding, P:lipid metabolic process, C:extracellular region, F:lipoprotein lipase activity, F:protein binding, P:lipid metabolic process, C:extracellular region, F:lipoprotein lipase activity, F:protein binding, P:lipid metabolic process, C:extracellular region, F:lipoprotein lipase activity, F:protein binding, P:lipid metabolic process, C:extracellular region, F:lipoprotein lipase activity, F:protein binding, P:lipid metabolic process, C:extracellular region, F:lipoprotein lipase activity, F:protein binding, P:lipid metabolic process, C:extracellular matrix, C:extracellular region, F:heparin binding, F:lipoprotein lipase activity, F:protein binding, F:triglyceride binding, P:lipid catabolic process, P:positive regulation of cholesterol storage, P:positive regulation of sequestering of triglyceride, P:response to cold, P:response to drug, P:triglyceride biosynthetic process, P:triglyceride homeostasis, C:extracellular region, F:lipoprotein lipase activity, F:protein binding, P:lipid metabolic process
UniProtCell membrane, Chylomicron, Complete proteome, Disulfide bond, Glycoprotein, GPI-anchor, Heparin-binding, Hydrolase, Lipid degradation, Lipid metabolism, Lipoprotein, Membrane, Nitration, Reference proteome, Secreted, Signal, VLDL
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)0.13< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)0.17< 0.05cDNA microarray17003339
Exp19070598aMus musculus36kidneywholeDiabetes (diabetic nephropathy)0.47< 0.05cDNA microarray19070598
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.330.01cDNA microarray19099603
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.340.03cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.310cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.330cDNA microarray19099603
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.05< 0.05RNA microarray21752957
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.2< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.04< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0< 0.05RNA microarray21752957
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.450.000468RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium