CKDdb-logoCKDdb - Molecule ID A1708

geneC1qg
nameComplement C1q subcomponent subunit C ( Precursor)
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
C1QC_RATP31722ENSRNOG00000012804362634Rn.2393120575, 613652

Functions and classifications

GOC:collagen trimer, C:extracellular region, P:complement activation, classical pathway, P:innate immune response, P:negative regulation of granulocyte differentiation, P:negative regulation of macrophage differentiation, C:collagen
UniProtCollagen, Complement pathway, Complete proteome, Direct protein sequencing, Disulfide bond, Hydroxylation, Immunity, Innate immunity, Reference proteome, Repeat, Secreted, Signal
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18187931aMus musculus20kidneyglomeruliGlomerulonephritis (lupus nephritis)22.8< 0.05RNA microarray18187931
Exp18187931bMus musculus18kidneyglomeruliGlomerulonephritis (lupus nephritis)8.1< 0.05RNA microarray18187931
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.690cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.720.02cDNA microarray19099603
Exp19398767Homo sapiens20kidneybiopsy sectionFibrosis (Interstitial fibrosis and tubular atrophy)2.230.0011234RNA microarray19398767
Exp20181666aMus musculus6kidney IRI (ischemic injury model)4.4< 0.05RNA microarray20181666
Exp20181666bMus musculus6kidney IRI (ischemic injury model)8.1< 0.05RNA microarray20181666
Exp20181666cMus musculus6kidney IRI (ischemic injury model)4.2< 0.05RNA microarray20181666
Exp20812764Homo sapiens13bloodplasmaTransplantation (Acute Renal Allograft Rejection)2.330.8755LC-MS/MS20812764
Exp20813037cRattus norvegicus6kidneywholePolycystic_Kidney_Disease (polycystic kidney disease)3.167.51E-08RNA microarray20813037
Exp21519365Mus musculus20kidneycortexGlomerulonephritis (glomerular hyperfiltration)2.07< 0.05cDNA microarray21519365
Exp21519365Mus musculus20kidneycortexGlomerulonephritis (glomerular hyperfiltration)2.07< 0.05cDNA microarray21519365
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)2.480.00774RNA microarray23291264
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.08< 0.05RNA-seq23757392
Exp24757019Mus musculus17kidneywholeGlomerulonephritis (lupus nephritis)2.70RNA microarray24757019

Compile date 08-10-2018© iMODE-CKD consortium