CKDdb-logoCKDdb - Molecule ID A1707

geneC1qb
nameComplement C1q subcomponent subunit B
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
C1QB_MOUSEP14106ENSMUSG0000003690512260Mm.2570120570, 613652

Functions and classifications

GOC:collagen trimer, C:extracellular region, F:protein homodimerization activity, P:complement activation, classical pathway, P:innate immune response, P:inner ear development
UniProtCollagen, Complement pathway, Complete proteome, Disulfide bond, Glycoprotein, Hydroxylation, Immunity, Innate immunity, Pyrrolidone carboxylic acid, Reference proteome, Repeat, Secreted, Signal
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18187931aMus musculus20kidneyglomeruliGlomerulonephritis (lupus nephritis)8< 0.05RNA microarray18187931
Exp18187931bMus musculus18kidneyglomeruliGlomerulonephritis (lupus nephritis)4.8< 0.05RNA microarray18187931
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)4.140.03cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)4.020.02cDNA microarray19099603
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)4.110.000226863RNA microarray20019191
Exp20181666aMus musculus6kidney IRI (ischemic injury model)4.2< 0.05RNA microarray20181666
Exp20181666bMus musculus6kidney IRI (ischemic injury model)7.6< 0.05RNA microarray20181666
Exp20181666cMus musculus6kidney IRI (ischemic injury model)4.1< 0.05RNA microarray20181666
Exp20813037cRattus norvegicus6kidneywholePolycystic_Kidney_Disease (polycystic kidney disease)3.172.39E-07RNA microarray20813037
Exp21519365Mus musculus20kidneycortexGlomerulonephritis (glomerular hyperfiltration)2.31< 0.05cDNA microarray21519365
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)29.53< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)24.42< 0.05RNA microarray21752957
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.68< 0.05RNA-seq23757392
Exp23760282aMus musculus kidneywholeureteral_obstruction (renal tubulointerstitial injury)0.460.007RNA microarray23760282
Exp24757019Mus musculus17kidneywholeGlomerulonephritis (lupus nephritis)3.290RNA microarray24757019
Exp25133636Homo sapiens22kidneyglomeruliGlomerulonephritis (IgA nephropathy (with endocapillary proliferation (E1)))6.040.0084RNA microarray25133636

Compile date 08-10-2018© iMODE-CKD consortium