CKDdb-logoCKDdb - Molecule ID A1630

geneCd59a, Cd59
nameCD59A glycoprotein
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CD59A_MOUSEO55186ENSMUSG0000003267912509Mm.247265107271, 612300

Functions and classifications

GOC:anchored component of membrane, C:external side of plasma membrane, C:extracellular region, F:complement binding, P:cell activation, P:negative regulation of activation of membrane attack complex, P:negative regulation of angiogenesis, P:negative regulation of complement activation, P:negative regulation of fibroblast growth factor production, P:negative regulation of vascular endothelial growth factor receptor signaling pathway, C:anchored to membrane
UniProtCell membrane, Complete proteome, Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein, Membrane, Reference proteome, Signal
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.82< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.61< 0.05cDNA microarray17003339
Exp18095357Homo sapiens38urinewholeGlomerulonephritis (IgA nephropathy)00.0001nano-HPLC-ESI-MS/MS18095357
Exp18440303Rattus norvegicus20urineglycoproteinsGlomerulonephritis (adriamycin nephropathy and Thy1.1 induced glomerulonephritis)>100 LC-MS/MS18440303
Exp19136817Mus musculus10kidneyglomeruliUrination_Disorders (proteinuria)0.410.00303RNA microarray19136817
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)2.99< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.3< 0.05RNA microarray21752957
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)1 nLC-ESI-UHR-QToF-MS/MS23344851
Exp23464927Homo sapiens10urine Fabry (12 months of ERT)0.92<0.05QTOF MS/MS23464927
Exp24067438Homo sapiens64urinewholeAKI (AKI)4< 0.05LC-ESI-MS/MS24067438
Exp24790760Homo sapiens19urinewholeGlomerulonephritis (focal segmental glomerulosclerosis)0.04 nLC-MS/MS24790760
Exp25032130Homo sapiens11urinewholeGlomerulonephritis (focal segmental glomerulosclerosis)7.21 nano-flow LC-MS/MS25032130
Exp25150443aHomo sapiens24urinesupernatantNephrotic_Syndrome (paediatric idiopathic nephrotic syndrome)54.90E-14LC-MS25150443
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.42.01E-04RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.45.43E-05RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium