CKDdb-logoCKDdb - Molecule ID A1628

geneC9
nameComplement component C9
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CO9_MOUSEP06683ENSMUSG0000002214912279Mm.29095120940, 613825

Functions and classifications

GOC:cytoplasm, C:extracellular region, C:membrane attack complex, P:complement activation, alternative pathway, P:complement activation, classical pathway, P:cytolysis, P:activation of cysteine-type endopeptidase activity involved in apoptotic process, P:blood coagulation, P:induction of apoptosis
UniProtCell membrane, Complement alternate pathway, Complement pathway, Complete proteome, Cytolysis, Disulfide bond, EGF-like domain, Glycoprotein, Immunity, Innate immunity, Membrane, Membrane attack complex, Reference proteome, Secreted, Signal, Transmembrane, Transmembrane beta strand
PADBtransmembrane

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp16083269Rattus norvegicus10bloodserumTransplantation (Acute Renal Allograft Rejection)up< 0.05SELDI-MS (CM10, Q10), MALDI-MS/MS16083269
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)2.390.05RNA microarray17579666
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)up MS/MS, LTQ LX linear ion trap20093355
Exp20812764Homo sapiens13bloodplasmaTransplantation (Acute Renal Allograft Rejection)10.190.0008LC-MS/MS20812764
Exp21544065aRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)1.790.002MALDI-TOF/TOF21544065
Exp21544065bRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)1.050.039MALDI-TOF/TOF21544065
Exp21544065cRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)1.340.021MALDI-TOF/TOF21544065
Exp22172726Homo sapiens20kidneyglomeruliDiabetes (type 2 diabetic nephropathy)2.830.0001QSTAR Elite LC-MS/MS22172726
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)5.85 nLC-ESI-UHR-QToF-MS/MS23344851
Exp25769567Homo sapiens19kidneygraftsChronic_rejection (Chronic_rejection)1.51< 0.05ESI-TOF/TOF25769567

Compile date 08-10-2018© iMODE-CKD consortium