CKDdb-logoCKDdb - Molecule ID A1627

geneC8G
nameComplement component C8 gamma chain precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CO8G_HUMANP07360ENSG00000176919733Hs.1285120930

Functions and classifications

GOC:extracellular region, C:extracellular space, C:membrane attack complex, F:retinol binding, P:complement activation, alternative pathway, P:complement activation, classical pathway, P:cytolysis, P:innate immune response, P:regulation of complement activation, C:extracellular region, P:innate immune response
UniProt3D-structure, Complement alternate pathway, Complement pathway, Complete proteome, Cytolysis, Direct protein sequencing, Disulfide bond, Immunity, Innate immunity, Membrane attack complex, Polymorphism, Pyrrolidone carboxylic acid, Reference proteome, Retinol-binding, Secreted, Signal
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.310.00363RNA microarray19698090
Exp20812764Homo sapiens13bloodplasmaTransplantation (Acute Renal Allograft Rejection)2.170.3236LC-MS/MS20812764
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.150.021124097NGS, RNA-seq.22266139
Exp23760282bMus musculus kidneywholeureteral_obstruction (renal tubulointerstitial injury)0.230.024RNA microarray23760282
Exp25769567Homo sapiens19kidneygraftsChronic_rejection (Chronic_rejection)2.32< 0.05ESI-TOF/TOF25769567

Compile date 08-10-2018© iMODE-CKD consortium