CKDdb-logoCKDdb - Molecule ID A1626

geneC8B
nameComplement component C8 beta chain precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CO8B_HUMANP07358ENSG00000021852732Hs.391835120960, 613789

Functions and classifications

GOC:extracellular region, C:extracellular space, C:membrane, C:membrane attack complex, P:complement activation, P:complement activation, alternative pathway, P:complement activation, classical pathway, P:cytolysis, P:innate immune response, P:regulation of complement activation, P:immune response, P:innate immune response"
UniProt3D-structure, Complement alternate pathway, Complement pathway, Complete proteome, Cytolysis, Direct protein sequencing, Disulfide bond, EGF-like domain, Glycoprotein, Immunity, Innate immunity, Membrane attack complex, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Secreted, Signal
PADBTM: transmembrane

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.327.44E-04RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.170.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium