CKDdb-logoCKDdb - Molecule ID A1624

geneC7
nameComplement component C7 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CO7_HUMANP10643ENSP00000322061730Hs.78065217070, 610102

Functions and classifications

GOC:extracellular region, C:membrane attack complex, P:cellular sodium ion homeostasis, P:complement activation, P:complement activation, alternative pathway, P:complement activation, classical pathway, P:cytolysis, P:innate immune response, P:regulation of complement activation, P:immune response, P:innate immune response
UniProt3D-structure, Complement alternate pathway, Complement pathway, Complete proteome, Cytolysis, Direct protein sequencing, Disease mutation, Disulfide bond, EGF-like domain, Glycoprotein, Immunity, Innate immunity, Membrane attack complex, Polymorphism, Reference proteome, Repeat, Secreted, Signal, Sushi
PADBDIS: disease

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)7.7< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)16.22< 0.05RNA microarray21752957
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)2.020.03556LC-MS/MS23228063
Exp25957429Homo sapiens21urinewholeGlomerulonephritis (IgA nephropathy)0.38<0.05nano-LC-MS/MS25957429

Compile date 08-10-2018© iMODE-CKD consortium